Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.981 162 2 1995 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.934 151 3 1991 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.956 114 2 1999 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.400 None 0.967 91 3 2001 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.400 None 0.956 90 3 2004 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.984 62 4 1993 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 31 2 2013 2020
Entrez Id: 284697
Gene Symbol: BTBD8
BTBD8 		Q5XKL5 BTB domain containing 8 125 0.547 0.692 6.1E-07 0.100 None 1.000 29 0 2004 2020
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.100 None 1.000 29 3 2003 2020
Entrez Id: 54210
Gene Symbol: TREM1
TREM1 		Q9NP99 triggering receptor expressed on myeloid cells 1 172 0.515 0.808 6.3E-03 0.100 None 0.920 25 2 2001 2020
Entrez Id: 133
Gene Symbol: ADM
ADM 		P35318 adrenomedullin Signaling 405 0.436 0.808 4.1E-02 0.400 None 1.000 23 0 2000 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 1.000 22 0 2011 2020
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.100 None 1.000 22 0 2008 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.100 None 1.000 18 1 2001 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 18 0 2014 2020
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.100 None 1.000 17 0 2001 2020
Entrez Id: 4827
Gene Symbol: NM
NM 		neutrophil migration 250 0.473 0.808 0.100 None 0.938 16 0 2012 2020
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.400 None 1.000 15 0 2000 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 1.000 14 0 2010 2020
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13 		Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 229 0.496 0.769 5.1E-15 0.100 None 1.000 12 0 2006 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 726 0.363 0.846 0.100 None 1.000 12 1 2011 2020
Entrez Id: 54106
Gene Symbol: TLR9
TLR9 		Q9NR96 toll like receptor 9 457 0.411 0.885 9.8E-06 0.100 None 0.917 12 1 2009 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.400 None 1.000 11 0 2005 2020
Entrez Id: 7450
Gene Symbol: VWF
VWF 		P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.090 None 1.000 9 0 2010 2020
Entrez Id: 79792
Gene Symbol: GSDMD
GSDMD 		P57764 gasdermin D 50 0.641 0.692 1.1E-13 0.090 None 1.000 9 0 2017 2020